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Catalyzed Carbonylation for Synthesis of Diethyl Malonates(PDF)

《南京理工大学学报》(自然科学版)[ISSN:1005-9830/CN:32-1397/N]

Issue:
2004年06期
Page:
658-662
Research Field:
Publishing date:

Info

Title:
Catalyzed Carbonylation for Synthesis of Diethyl Malonates
Author(s):
LU Ya-lin 1SONG Wei-hong 2
1.School of Chemical Engineering,NUST,Nanjing 210094,China; 2.Shanghai Research Institute of Petrochemical Industry,China Petroleum and Chemical Corporation, Shanghai 201208,China
Keywords:
diethyl malonate carbonylation ethyl chloroacetate reaction kinetics reaction mechanism
PACS:
O623
DOI:
-
Abstract:
Tetracarbonyl cobaltate sodium synthesized in situ was used as the catalyst for carbonylation of ethyl chloroacetate under mildness condit ion. Diethyl malonate were obtained in high selectivity and yields. Effects of reaction temperature, CO pressure and alkali reagent on react ion were discussed. Relative reaction kinetics and possible mechanism were also indicated. Carbonylat ion of ethyl chloroacetate is a pseudo-firs-t order react ion. The results show that this new simple technique has many advantages such as high selectivity, no pollution and environmental friendliness.

References:

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Memo

Memo:
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Last Update: 2013-03-11