[1]李宗安,朱 丽,章维一.微流体脉冲惯性驱动-控制用T型玻璃微喷嘴 设计及实验[J].南京理工大学学报(自然科学版),2014,38(06):795.
 Li Zongan,Zhu Li,Zhang Weiyi.Design and experiment of T-shape glass micro-nozzle used in pulse driving-controlling of micro-fluids[J].Journal of Nanjing University of Science and Technology,2014,38(06):795.

微流体脉冲惯性驱动-控制用T型玻璃微喷嘴 设计及实验




Design and experiment of T-shape glass micro-nozzle used in pulse driving-controlling of micro-fluids
李宗安朱 丽章维一
南京理工大学 机械工程学院,江苏 南京 210094
Li ZonganZhu LiZhang Weiyi
School of Mechanical Engineering,NUST,Nanjing 210094,China
微流体数字化 脉冲惯性驱动-控制 T型玻璃微喷嘴 冷热加工工艺 拉力 线圈温度 延时时间 线圈宽度 序列乳液 微胶囊
microfluidic digitalization pulse driving-controlling T-shape glass micro-nozzles hot-cold fabricating process pull force coil temperature delay time coil width orderly emulsion microcapsules
为了简化用于微流体脉冲惯性驱动-控制的T型玻璃微喷嘴的制作工艺,设计制作了重力式玻璃微喷嘴制作仪、微孔制作仪。研究了拉力、线圈温度、延时时间、线圈宽度对拉制工艺,加热时间、进给量对锻制工艺,加热面积对微孔制作工艺的影响规律。制作了微喷嘴、微管道、玻璃微孔等基本微流体器件并以紫外线(UV)光学胶水密封组合,设计制作了T型玻璃微喷嘴。设计了拉锻集成式玻璃微流体器件制作设备,其拉制工艺延时控制结构比非延时控制结构制作的微喷嘴锥长可减小3.5 mm。微孔制作仪可在玻璃毛细管侧壁开制400 μm圆形微孔。制作了序列玉米胚芽油海藻酸钠水油(W-O)乳液和500 μm左右的单、双颗玉米胚芽油微胶囊,其粒径均匀、形态良好。结果表明,基于冷热加工工艺及组合工艺可以制作结构简单、生物化学性能和光学性能良好的T型组合玻璃微流体器件,基于脉冲惯性驱动可以产生多相流体脉冲流动及微喷射。
In order to simplify the fabrication process of T-shape glass micro-nozzles used in pulse driving-controlling of micro-fluids,a novel gravity based glass micro-nozzle preparation apparatus and a micro hole fabrication apparatus are designed and fabricated.The impact laws of pull force,coil temperature,delay time,coil width on pulling process,heating time,feed distance on forging process,and heating area on micro hole fabrication process are researched experimentally.Borosilicate glass microfluidic devices such as micro-nozzle,micro-channel,micro hole in the glass capillary wall are prepared.Sealed by ultraviolet rays(UV)optical glue,a kind of T-shape glass micro-nozzle is designed and prepared.A glass microfluidic device preparation apparatus integrating forging and pulling process is designed.The tape length of the micro-nozzle fabricated by the pulling process with delay control structure is 3.5 mm shorter than that fabricated by the pulling process without delay control structure.400 μm circular micro holes can be fabricated on the glass pipe wall by the micro hole fabrication apparatus.Orderly core oil emulsion in sodium alginate solution and 500 μm microcapsules with single or double core oil are prepared uniformly and well.Results show that T-shape combined glass microfluidic devices could be fabricated by hot-cold fabricating process and have the advantage of simple structure,low cost,good bio-chemical and optical characters,and the T-shape glass micro-nozzle driven by pulse inertia force could be used to prepare pulse fluid flow and micro injection.


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收稿日期:2013-03-06 修回日期:2014-02-10
基金项目:国家自然科学基金(51175268; 11102090); 江苏省三维打印重点实验室开放基金(L2014071302)
作者简介:李宗安(1986-),男,博士生,主要研究方向:微流体系统和微流体器件制造技术,E-mail:ethan301@163.com; 通讯作者:朱丽(1977-),女,副研究员,主要研究方向:微系统与生物制造工程,E-mail:nlgzl@163.com。
更新日期/Last Update: 2014-12-31